Es radiológicamente un problema la diferenciación por Resonancia Magnética, Tomografía y Ultrasonido de la hiperplasia focal nodular y la de un Hepatocarcinoma en pacientes con Cirrosis.
Se practicó una revisión de 304 pacientes con hiperplasia focal nodular y se utilizó un nuevo medio de contraste llamado “GADOXETIC ACID – ENHANCED MAGNETIC RESONANCE IMAGING”, únicamente disponible en Europa y países asiáticos. TecniScan Guatemala está tratando de comprar este nuevo medio de contraste, en Europa.
La gran mayoría (94-97%) de hiperplasia focal nodular mostraron una señal alta o isointensa lo que permite distinguirlos de los Hepatocarcinomas. Las reacciones alérgicas son mínimas tipo rash, nausea, vómitos, cefalea y ligera hipotensión arterial.
Artículo proveniente de la Universidad de Ulsan, Korea y Centro Asiático de Hígado de la misma Universidad.
La gran mayoría (94-97%) de hiperplasia focal nodular mostraron una señal alta o isointensa lo que permite distinguirlos de los Hepatocarcinomas. Las reacciones alérgicas son mínimas tipo rash, nausea, vómitos, cefalea y ligera hipotensión arterial.
Artículo proveniente de la Universidad de Ulsan, Korea y Centro Asiático de Hígado de la misma Universidad.
Muy atentamente, equipo TecniScan Científico.
Artículo de Referencia
The Diagnostic value of Gd-EOB-DTPA-MRI for the diagnosis of focal nodular hyperlapsia: a systematic review and meta-analysis.
Eur Radiol (2015) 25: 950
OBJECTIVE
We aimed to systematically review the gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-MRI) findings of focal nodular hyperplasia (FNH) and its diagnostic value.
METHODS
A thorough literature search was conducted in Ovid-MEDLINE and EMBASE databases to identify studies evaluating Gd-EOB-DTPA-MRI findings of FNH. To evaluate the frequency of characteristic imaging findings on Gd-EOB-DTPA-MRI, pooled proportions of high/iso signal intensity (SI) on the hepatobiliary phase (HBP), arterial enhancement, high/iso SI on the portal-venous phase (PVP) or equilibrium phase (EP), and the central scar were calculated. Meta-analysis was performed to evaluate the diagnostic accuracy of high/iso SI on HBP for distinguishing FNH from hepatocellular adenoma.
RESULTS
A review of 96 articles identified ten eligible articles with 304 patients with FNHs for meta-analysis. Pooled proportion of the Gd-EOB-DTPA-MRI findings showed that high/iso SI on the HBP, arterial enhancement, and high/iso SI on the PVP/EP were observed in 93% (95% CI, 90-97%), 99% (95% CI, 97-100%), and 97% (95% CI, 95-99%) of FNHs, respectively, while a central scar was observed in 61% of FNHs (95% CI, 47-74%). High/iso SI on the HBP was highly accurate for distinguishing FNH from hepatocellular adenoma, with a summary sensitivity of 93.9% (95% CI, 89.1-97.1%) and a specificity of 95.3% (95% CI, 88.4-98.7%).
CONCLUSIONS
High/iso SI on the HBP of Gd-EOB-DTPA-MRI is characteristic and a prevalent finding of FNHs and can be helpful in the management of patients with FNH.
The Diagnostic value of Gd-EOB-DTPA-MRI for the diagnosis of focal nodular hyperlapsia: a systematic review and meta-analysis.
Eur Radiol (2015) 25: 950
OBJECTIVE
We aimed to systematically review the gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-MRI) findings of focal nodular hyperplasia (FNH) and its diagnostic value.
METHODS
A thorough literature search was conducted in Ovid-MEDLINE and EMBASE databases to identify studies evaluating Gd-EOB-DTPA-MRI findings of FNH. To evaluate the frequency of characteristic imaging findings on Gd-EOB-DTPA-MRI, pooled proportions of high/iso signal intensity (SI) on the hepatobiliary phase (HBP), arterial enhancement, high/iso SI on the portal-venous phase (PVP) or equilibrium phase (EP), and the central scar were calculated. Meta-analysis was performed to evaluate the diagnostic accuracy of high/iso SI on HBP for distinguishing FNH from hepatocellular adenoma.
RESULTS
A review of 96 articles identified ten eligible articles with 304 patients with FNHs for meta-analysis. Pooled proportion of the Gd-EOB-DTPA-MRI findings showed that high/iso SI on the HBP, arterial enhancement, and high/iso SI on the PVP/EP were observed in 93% (95% CI, 90-97%), 99% (95% CI, 97-100%), and 97% (95% CI, 95-99%) of FNHs, respectively, while a central scar was observed in 61% of FNHs (95% CI, 47-74%). High/iso SI on the HBP was highly accurate for distinguishing FNH from hepatocellular adenoma, with a summary sensitivity of 93.9% (95% CI, 89.1-97.1%) and a specificity of 95.3% (95% CI, 88.4-98.7%).
CONCLUSIONS
High/iso SI on the HBP of Gd-EOB-DTPA-MRI is characteristic and a prevalent finding of FNHs and can be helpful in the management of patients with FNH.
Comité Editorial: Grupo de Radiológicos TecniScan.
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