Por medio de la Tomografía computarizada de Arterias Coronarias hoy en día se puede diagnosticar área de estenosis, sin embargo, no se podía determinar si la estenosis es hemodinamicamente isquémica significativa.
Hoy en día con los nuevos Tomógrafos que en solo una pulsación del corazón producen imágenes en segunda, tercera y cuarta dimensión, ya es también posible determinar la reserva de fracción de flujo.
La reserva de fracción de flujo es la relación entre la presión de la arteria coronaria distal al área de estenosis, comparada con la presión aórtica promedio y representa una medida fisiológica funcional de la estenosis.
El artículo que le enviamos fue realizado en Cuatro universidades: Carolina del Sur, Estados Unidos; Heidelberg, Alemania; Beijing, China y Giessen, Alemania. El estudio compara los hallazgos obtenidos por Tomografía con los hallazgos obtenidos en los mismos pacientes por medio de Arteriografía Invasiva que se considera el procedimiento ideal.
Se encontró una sensitividad de 98% y un valor predictivo negativo del 100%.
Los nuevos Tomógrafos Computarizados Helicoidales obtienen un examen de Coronarias, Corazón aorta y arteria pulmonar en un tiempo de exposición de 0.28 de segundos.
La reserva de fracción de flujo es la relación entre la presión de la arteria coronaria distal al área de estenosis, comparada con la presión aórtica promedio y representa una medida fisiológica funcional de la estenosis.
El artículo que le enviamos fue realizado en Cuatro universidades: Carolina del Sur, Estados Unidos; Heidelberg, Alemania; Beijing, China y Giessen, Alemania. El estudio compara los hallazgos obtenidos por Tomografía con los hallazgos obtenidos en los mismos pacientes por medio de Arteriografía Invasiva que se considera el procedimiento ideal.
Se encontró una sensitividad de 98% y un valor predictivo negativo del 100%.
Los nuevos Tomógrafos Computarizados Helicoidales obtienen un examen de Coronarias, Corazón aorta y arteria pulmonar en un tiempo de exposición de 0.28 de segundos.
Muy atentamente, equipo TecniScan Científico.
Artículo de Referencia
Coronary CT angiography-derived fractional flow reserve correlated with invasive fractional flow reserve measurements--initial experience with a novel physician-driven algorithm.
eur radiol 2015, 25:4: 1201-1207
OBJECTIVES
The present study aimed to determine the feasibility of a novel fractional flow reserve (FFR) algorithm based on coronary CT angiography (cCTA) that permits point-of-care assessment, without data transfer to core laboratories, for the evaluation of potentially ischemia-causing stenoses.
METHODS
To obtain CT-based FFR, anatomical coronary information and ventricular mass extracted from cCTA datasets were integrated with haemodynamic parameters. CT-based FFR was assessed for 36 coronary artery stenoses in 28 patients in a blinded fashion and compared to catheter-based FFR. Haemodynamically relevant stenoses were defined by an invasive FFR ≤0.80. Time was measured for the processing of each cCTA dataset and CT-based FFR computation. Assessment of cCTA image quality was performed using a 5-point scale.
RESULTS
Mean total time for CT-based FFR determination was 51.9 ± 9.0 min. Per-vessel analysis for the identification of lesion-specific myocardial ischemia demonstrated good correlation (Pearson's product-moment r = 0.74, p < 0.0001) between the prototype CT-based FFR algorithm and invasive FFR. Subjective image quality analysis resulted in a median score of 4 (interquartile ranges, 3-4). CONCLUSIONS Our initial data suggest that the CT-based FFR method for the detection of haemodynamically significant stenoses evaluated in the selected population correlates well with invasive FFR and renders time-efficient point-of-care assessment possible. KEY POINTS: • CT-based FFR computation is a promising novel non-invasive application. • A novel prototype algorithm permits time-efficient point-of-care CT-based FFR assessment. • Initial results of the CT-based FFR prototype algorithm compare favourably with FFR.
Coronary CT angiography-derived fractional flow reserve correlated with invasive fractional flow reserve measurements--initial experience with a novel physician-driven algorithm.
eur radiol 2015, 25:4: 1201-1207
OBJECTIVES
The present study aimed to determine the feasibility of a novel fractional flow reserve (FFR) algorithm based on coronary CT angiography (cCTA) that permits point-of-care assessment, without data transfer to core laboratories, for the evaluation of potentially ischemia-causing stenoses.
METHODS
To obtain CT-based FFR, anatomical coronary information and ventricular mass extracted from cCTA datasets were integrated with haemodynamic parameters. CT-based FFR was assessed for 36 coronary artery stenoses in 28 patients in a blinded fashion and compared to catheter-based FFR. Haemodynamically relevant stenoses were defined by an invasive FFR ≤0.80. Time was measured for the processing of each cCTA dataset and CT-based FFR computation. Assessment of cCTA image quality was performed using a 5-point scale.
RESULTS
Mean total time for CT-based FFR determination was 51.9 ± 9.0 min. Per-vessel analysis for the identification of lesion-specific myocardial ischemia demonstrated good correlation (Pearson's product-moment r = 0.74, p < 0.0001) between the prototype CT-based FFR algorithm and invasive FFR. Subjective image quality analysis resulted in a median score of 4 (interquartile ranges, 3-4). CONCLUSIONS Our initial data suggest that the CT-based FFR method for the detection of haemodynamically significant stenoses evaluated in the selected population correlates well with invasive FFR and renders time-efficient point-of-care assessment possible. KEY POINTS: • CT-based FFR computation is a promising novel non-invasive application. • A novel prototype algorithm permits time-efficient point-of-care CT-based FFR assessment. • Initial results of the CT-based FFR prototype algorithm compare favourably with FFR.
Comité Editorial: Grupo de Radiológicos TecniScan.
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