• Se realizó un estudio comparativo entre el método manual y uno computarizado para medir el volumen de un infarto isquémico cerebral.
• El estudio incluyó 34 pacientes consecutivos con un infarto Isquémico, la mayor parte por obstrucciones de la arteria cerebral media.
• Dos NeuroRadiólogos con años de experiencia practicaron medidas del infarto en forma manual y computarizada, comparando los resultados obtenidos por ambos métodos.
• Todos los estudios fueron realizados con Tomografías de 64 cortes o más, utilizando 5 mm. de espesor de corte, reconstrucciones de 0.6 y 1 mm., en proyecciones axial, sagital y coronal.
• El presente estudio reveló que existe una excelente correlación entre ambos métodos, con la única diferencia que el método manual lleva ligeramente más tiempo. (Ver artículo sobre Medición de Infarto por el Método ABC/2, que se publica en TecniScan Científico).
• El artículo proviene del Instituto de Investigación Cerebral de la Universidad de Amsterdam, Universidad Twente, Enschede, y Erasmus Medical Center, todos de Holanda.
• Dos NeuroRadiólogos con años de experiencia practicaron medidas del infarto en forma manual y computarizada, comparando los resultados obtenidos por ambos métodos.
• Todos los estudios fueron realizados con Tomografías de 64 cortes o más, utilizando 5 mm. de espesor de corte, reconstrucciones de 0.6 y 1 mm., en proyecciones axial, sagital y coronal.
• El presente estudio reveló que existe una excelente correlación entre ambos métodos, con la única diferencia que el método manual lleva ligeramente más tiempo. (Ver artículo sobre Medición de Infarto por el Método ABC/2, que se publica en TecniScan Científico).
• El artículo proviene del Instituto de Investigación Cerebral de la Universidad de Amsterdam, Universidad Twente, Enschede, y Erasmus Medical Center, todos de Holanda.
Muy atentamente, equipo TecniScan Científico.
Artículo de Referencia:
Automated cerebral infarct volume measurement in follow-up noncontrast CT scans of patients with acute ischemic stroke.
AJNR Am J Neuroradiol. 2013 Aug;34(8):1522-7
Background and Purpose
Cerebral infarct volume as observed in follow-up CT is an important radiologic outcome measure of the effectiveness of treatment of patients with acute ischemic stroke. However, manual measurement of CIV is time-consuming and operator-dependent. The purpose of this study was to develop and evaluate a robust automated measurement of the CIV.
Materials and Methods
The CIV in early follow-up CT images of 34 consecutive patients with acute ischemic stroke was segmented with an automated intensity-based region-growing algorithm, which includes partial volume effect correction near the skull, midline determination, and ventricle and hemorrhage exclusion. Two observers manually delineated the CIV. Interobserver variability of the manual assessments and the accuracy of the automated method were evaluated by using the Pearson correlation, Bland-Altman analysis, and Dice coefficients. The accuracy was defined as the correlation with the manual assessment as a reference standard.
Results
The Pearson correlation for the automated method compared with the reference standard was similar to the manual correlation (R = 0.98). The accuracy of the automated method was excellent with a mean difference of 0.5 mL with limits of agreement of -38.0-39.1 mL, which were more consistent than the interobserver variability of the 2 observers (-40.9-44.1 mL). However, the Dice coefficients were higher for the manual delineation.
Conclusions
The automated method showed a strong correlation and accuracy with the manual reference measurement. This approach has the potential to become the standard in assessing the infarct volume as a secondary outcome measure for evaluating the effectiveness of treatment.
Automated cerebral infarct volume measurement in follow-up noncontrast CT scans of patients with acute ischemic stroke.
AJNR Am J Neuroradiol. 2013 Aug;34(8):1522-7
Background and Purpose
Cerebral infarct volume as observed in follow-up CT is an important radiologic outcome measure of the effectiveness of treatment of patients with acute ischemic stroke. However, manual measurement of CIV is time-consuming and operator-dependent. The purpose of this study was to develop and evaluate a robust automated measurement of the CIV.
Materials and Methods
The CIV in early follow-up CT images of 34 consecutive patients with acute ischemic stroke was segmented with an automated intensity-based region-growing algorithm, which includes partial volume effect correction near the skull, midline determination, and ventricle and hemorrhage exclusion. Two observers manually delineated the CIV. Interobserver variability of the manual assessments and the accuracy of the automated method were evaluated by using the Pearson correlation, Bland-Altman analysis, and Dice coefficients. The accuracy was defined as the correlation with the manual assessment as a reference standard.
Results
The Pearson correlation for the automated method compared with the reference standard was similar to the manual correlation (R = 0.98). The accuracy of the automated method was excellent with a mean difference of 0.5 mL with limits of agreement of -38.0-39.1 mL, which were more consistent than the interobserver variability of the 2 observers (-40.9-44.1 mL). However, the Dice coefficients were higher for the manual delineation.
Conclusions
The automated method showed a strong correlation and accuracy with the manual reference measurement. This approach has the potential to become the standard in assessing the infarct volume as a secondary outcome measure for evaluating the effectiveness of treatment.
Comité Editorial: Grupo de Radiológicos TecniScan.
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